What is a homocysteine test?
A homocysteine test measures the amount of homocysteine in your blood. Homocysteine is a type of amino acid, a chemical your body uses to make proteins. Normally, vitamin B12, vitamin B6, and folic acid break down homocysteine and change it into other substances your body needs. There should be very little homocysteine left in the bloodstream. If you have high levels of homocysteine in your blood, it may be a sign of a vitamin deficiency, heart disease, or a rare inherited disorder.
Other names: total homocysteine, plasma total homocysteine
What is it used for?
A homocysteine test may be used to:
- Find out if you have deficiency in vitamin B12, B6, or folic acid.
- Help diagnose homocystinuria, a rare, inherited disorder that prevents the body from breaking down certain proteins. It can cause serious health problems and usually starts in early childhood. Most U.S. states require all infants to get a homocysteine blood test as part of routine newborn screening.
- Screen for heart disease in people at high risk for heart attack or stroke
- Monitor people who have heart disease.
Why do I need a homocysteine test?
You may need this test if you have symptoms of a vitamin B or folic acid deficiency. These include:
- Dizziness
- Weakness
- Fatigue
- Pale skin
- Sore tongue and mouth
- Tingling in the hands, feet, arms, and/or legs (in vitamin B12 deficiency)
You may also need this test if you are at high risk for heart disease because of prior heart problems or a family history of heart disease. Excess levels of homocysteine can build up in the arteries, which may increase your risk of blood clots, heart attack, and stroke.
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