Sunday, May 29, 2022

Cannabis and Parkinson's Disease - cannabis good for nausea, pain, anxiety

https://www.youtube.com/watch?v=e6dD81GhgiI&ab_channel=DemystifyingMedicine
Cannabis and Parkinson's Disease - cannabis good for nausea, pain, anxiety

2:52  some PD folks fail to respond to L-dopa and it has adverse effects.   3:53  2014 study found deficiency of GPR6 lead to increase of dopamine thus reduced dyskinesias caused by L-dopa treatment.  4:30  2017 study found CBD acts as an inverse agonist to GPR6 by binding to it which then increases dopamine in the brain thus reduces dyskinesias and motor symptoms of PD without negative side effects of L-dopa. 5:30  some PD CBD patients noted reduction in motor, non-motor, cognitive and mood symptoms. 5:50  physicians surveyed for evidence-based support rated CBD: 87% for nausea, 86% for pain, 60% for anxiety.
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