Genetic SNP Testing — SNPs are copying errors in the DNA. To make new cells, an existing cell divides in two, but first it copies its DNA so the new cell will have its own complete set of genetic instructions. Mistakes made during this copying process are called SNP errors (single nucleotide polymorphisms). Genetic SNP testing will look for copying errors on the DNA and dig deeper than laboratory studies that routinely look at only one or two of the positions associated with the MTHFR gene mutations — position 677 (the most common) and position 1298. The C677T mutation is commonly associated with cardiovascular problems and the A1298T mutation is associated with neurologic conditions.
These standard tests fall short in that our genes do not work in isolation and there are many other genes along the methylation genetic pathway that affect genetic expression. To get real valuable actionable testing you should have the other genes in the methylation pathway tested (www.23andme.com is the most affordable and complete testing today on the market).
Organic Acid Test — This is a simple urine test that investigates biomarkers from various metabolic pathways that can give a look at several body systems and provide an analysis of any nutritional deficiencies that might exist. Many functional medicine practitioners lean towards organic acid tests because they believe they provide the most useful data for dollars spent of any metabolic test. ...
When specific organic acids are found in organic acid testing, it may signal a metabolic insufficiency, which could be related to toxicity, a nutritional deficiency, or a hereditary enzyme deficit.
The information provided by organic acid testing can lead to great improvements in numerous other health conditions, including: sleep problems, fatigue, mood swings, weight gain, nausea, joint pain, acid reflux, auto immune disorders, depression, inflammation, headaches, acne/eczema, cancer, and many others.
In our next article, we'll take a look at other genes that play a significant role in methylation.
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